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J Interferon Cytokine Res ; 40(9): 443-445, 2020 09.
Article in English | MEDLINE | ID: covidwho-690435

ABSTRACT

The current pandemic of COVID-19 and the identification of accessible biomarkers of disease progression is of clinical importance in the management of this novel and serious disease. This study was completed to provide information regarding 1 possible uniquely upregulated marker in this illness, eosinophil-derived neurotoxin (EDN-1). A literature search was undertaken to provide medical data regarding EDN-1 as a biomarker in the clinical setting. The literature identified was further analyzed to identify its use in the clinical setting of viral disease and asthma.


Subject(s)
Alveolar Epithelial Cells/metabolism , Coronavirus Infections/pathology , Eosinophil-Derived Neurotoxin/metabolism , Pneumonia, Viral/pathology , Betacoronavirus , Biomarkers/analysis , COVID-19 , Cytokine Release Syndrome/pathology , Eosinophils/metabolism , Humans , Pandemics , SARS-CoV-2 , Transcriptome/genetics
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